Aldolase is an enzyme that is found in most tissues of the body. It helps convert glucose into energy. It is found throughout the body and is elevated in the bloodstream when a patient has muscle or liver damage.

In the past, the aldolase blood test was ordered to diagnose and monitor certain conditions related to skeletal muscle and/or liver disease. It largely has been replaced by other enzyme tests such as CK (creatine kinase), ALT (alanine aminotransferase), and AST (aspartate aminotransferase), which are more specific indicators of muscle or liver damage. The aldolase test still is used a little in the monitoring of patients with muscular dystrophy.

A large number of medications also cause elevations of this enzyme.


A short period of fasting will provide more accurate results. A blood sample is taken by a needle from a vein.


  • 0-30 Days: 6.0-32.0 U/L

  • 1 month-6 years: 3.0-12.0 U/L

  • 7-17 years: 3.3-9.7 U/L

  • 18 Years and Older: 1.5-8.1 U/L

Ranges for normal findings may vary among different laboratories and hospitals. You should always check with your doctor after having lab work or other tests done to discuss the meaning of your test results and whether your values are considered within normal limits.


Your caregiver will go over the test results with you and discuss the importance and meaning of your results, as well as treatment options and the need for additional tests if necessary.


It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.