Somatropin, E coli derived (Injection)
Somatropin, E-Coli Derived (soe-ma-TROE-pin, E-KOH-lye dee-rived)
Treats certain conditions in which a person's body does not grow properly or does not produce enough natural growth hormone. This medicine is also used with a special nutrition program to treat short bowel syndrome.
Genotropin Miniquick, Omnitrope, Genotropin, Tev-Tropin, Humatrope, Nutropin, Nutropin AQ NuSpin 20, Nutropin AQ Pen, Nutropin AQ NuSpin 5, Nutropin AQ NuSpin 10, Nutropin AQ, Nutropin AQ Pen Cartridge, Norditropin Flexpro, Norditropin NordiFlex, Norditropin NordiflexThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have had an allergic reaction to somatropin, growth hormone, or benzyl alcohol. You should not use this medicine if you have cancer, are receiving cancer treatments, or have a severe illness after having surgery or a major medical emergency. You should not receive this medicine if you have eye problems caused by diabetes. You also should not receive this medicine if you have Prader-Willi syndrome and you are also severely overweight, or if you have severe breathing problems. Do not use this medicine if you or your child's normal bone growth has stopped (closed epiphyses).
How to Use This Medicine:
- Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.
- A nurse or other trained health professional will give you this medicine.
- You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
- This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. There are many different types of injection devices available for this medicine. Read all instructions carefully to be sure you know how to use your device.
- Each time you get your medicine, check to be sure you have received the proper device. Talk to your pharmacist if you have questions about the device that you were given.
- You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
- Use a new needle and syringe each time you inject your medicine.
- You might not use all of the medicine in each vial (glass container) or prefilled syringe. Use each vial or syringe only one time. Do not save an open vial or syringe. If the medicine in the vial or syringe has changed color, or if you see particles in it, do not use it.
- Use only the brand of this medicine that your doctor prescribed. Different brands may not work the same way.
If a dose is missed:
- Call your doctor or pharmacist for instructions.
How to Store and Dispose of This Medicine:
- If you store this medicine at home, keep it in the refrigerator. Do not freeze. If you are using Zorbtive?, store your medicine at room temperature, away from heat and direct light.
- You may keep the Genotropin Miniquick device in the refrigerator or at room temperature, away from heat, moisture, and direct light.
- Store Accretropin and Humatrope in the refrigerator for up to 14 days after its first use. Do not freeze or shake.
- Once the powder medicine has been mixed with the liquid, this mixture must be stored in the refrigerator. Zorbtive? that has been mixed should be used within 2 weeks. Genotropin that has been mixed should be used within 24 hours. Make sure you understand how long you can store the medicine after it has been mixed. Throw away any mixed medicine that has not been used within these timelines.
- After a Norditropin cartridge has been placed into the NordiPen device, you must store the pen in the refrigerator. Use the medicine in this pen within 4 weeks or it will expire and must be thrown away.
- Once the powder medicine has been mixed with the liquid, this mixture must be stored in the refrigerator. Humatrope cartridges that has been mixed should be used within 28 days or it will expire and must be thrown away.
- Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Make sure your doctor knows if you are using cyclosporine (Gengraf, Neoral, Sandimmune), an oral estrogen hormone replacement, a steroid medicine (such as dexamethasone, prednisolone, prednisone, or Medrol), or medicine for seizures (such as Depakote, Dilantin, Keppra?, Luminal, or Tegretol). Tell your doctor if you are also using insulin or diabetes medicine that you take by mouth (such as glyburide, metformin, Actos, Amaryl, Avandia, or Glucotrol).
Warnings While Using This Medicine:
- Make sure your doctor knows if you are pregnant or breastfeeding. Tell your doctor if you have thyroid problems, pituitary problems, or a history of cancer or scoliosis (curved spine). Tell your doctor if you are allergic to benzyl alcohol or a preservative called m-cresol.
- Make sure your child's doctor knows if your child has a history of ear infection.
- This medicine may cause a serious allergic reaction that requires immediate medical attention. Tell your doctor right away if you have a rash; itching; swelling of the face, tongue, or throat; trouble with breathing; or chest pain after you receive the medicine.
- This medicine may cause a dislocation in the hip bone, especially in patients with growth hormone deficiency or Turner syndrome. Check with your doctor right away if you or your child has a limp or pain in the hip or knee.
- This medicine may raise or lower your blood sugar. Make sure your doctor knows if you have diabetes or a family history of diabetes.
- This medicine may cause an increased pressure in the head. Check with your doctor immediately if headache, nausea, vomiting, blurred vision, or any other change in vision occurs during treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).
- Make sure any doctor who treats you knows that you are using this medicine, especially if you need to be in the hospital for another illness.
- This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
- Talk with your doctor if you think you are growing too fast or that your growth has slowed down after using the medicine for several weeks.
- Tell your child's doctor if your child shows signs of early sexual development while using this medicine. This may include early breast development, increased genital size, growth of pubic hair, increased jaw size, or a change in face shape.
- This medicine may cause fluid retention (extra water in the body). Tell your doctor if you have burning, numbness, pain, or tingling in all fingers except the smallest finger; swelling of the hands and feet; or pain, swelling, or stiffness of the muscles. Your doctor may adjust your dose to reduce these side effects.
- Pancreatitis has occurred rarely in some patients who receive this medicine. Tell your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness.
- Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.
- Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Curved spine.
- Headache, pain behind your eyes, vision problems, and nausea or vomiting.
- Increased thirst or hunger, increase in how much or how often you urinate.
- Joint pain or limping.
- Numbness, tingling, or burning pain in your hands, arms, legs, or feet.
- Rapid growth or weight gain.
- Sudden and severe stomach pain, nausea, vomiting, fever, and lightheadedness.
- Swelling in your hands, legs, ankles, or feet.
- Unusual bleeding, bruising, or weakness.
If you notice these less serious side effects, talk with your doctor:
- Acne or pimples.
- Earache or swelling in the ear.
- Increased sweating.
- Muscle pain or stiffness.
- Numbness or tingling in your hands or fingers.
- Pain, redness, burning, swelling, a hard lump, or skin changes where your shot is given.
- Stomach pain, passing gas, or bowel problems.
- Stuffy or runny nose.
- Swelling of the breasts or breast soreness in both females and males.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
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