Allogeneic Blood Stem-Cell Transplant
After your initial induction therapy, you generally receive consolidation therapy. However, in some cases, your physician may suggest you consider receiving blood stem-cell transplant in place of consolidation therapy.
Blood stem-cell transplant is a procedure to replace your leukemic bone marrow with healthy bone marrow stem cells. An allogeneic transplant (ALLO) involves removing bone marrow from a matched donor. Allo means “other.”
The Process of an ALLO Transplant
- Blood stem cells are removed from your body and discarded.
- While hospitalized, you then receive intensive, high-dose chemotherapy, killing leukemic cells.
- Healthy stem cells are then transplanted from a matched donor.
- You will be in the hospital several weeks.
- It’s a high-risk procedure appropriate for only certain patients.
Factors That Impact Whether You Are a Candidate for ALLO Transplant
- The likelihood chemotherapy alone will cure your leukemia
- The type of gene changes you have
- The availability of a healthy donor (e.g., brother, sister; member of Bone Marrow Registry)
- Your overall health
- Your heart health
- Your kidney health
- Whether you can tolerate the intense chemotherapy
- Your personal preference
If we can get the disease under control with induction therapy, we can then come back and do the ALLO transplant as a way of ultimately controlling the disease.
Scott & White does not offer allogeneic blood stem-cell transplants. (We do offer autologous transplants, but those have not proven helpful in most cases of leukemia.)
All allogeneic blood stem-cell transplants are referred to one of our accredited partners in the state.