Chemotherapy for Renal Pelvis & Ureter Cancer

How Chemotherapy Is Administered

Chemotherapy drugs are generally administered in three ways:

  • By mouth in the form of a pill you swallow
  • By injection
  • Locally (directly to the tumor site)

Injection methods include:

  • Intra-arterial (IA): into an artery
  • Intramuscular (IM): into a muscle
  • Intravenous (IV): into a vein
  • Subcutaneous (SubQ): into the skin

Local/direct methods include:

  • Intracavitary: in the cavity (or space) where your tumor had been prior to surgery
  • Interstitial: into body tissue
  • Intraperitoneal: into your abdomen or peritoneal cavity (intestines, liver, stomach, ovaries)
  • Intrathecal: into the fluid-filled space surrounding your brain and spinal cord
  • Intratumoral: into the tumor
  • Intraventicular: into a ventricle
  • Convection-enhanced delivery: into your tumor using gravity or controlled flow

Chemotherapy is a form of cancer treatment where high-powered medications are used to kill cancer cells. It’s a systemic approach to cancer treatment, where drugs are delivered through your bloodstream, targeting cancer cells throughout your body.

Scott & White’s Approach

Our approach at Scott & White is in individualizing therapy.

Our medical oncologists take meticulous care to determine which chemotherapy drug or drugs are best for you. Several factors impact their decision, including the type, location and stage of your specific tumor and your overall medical condition. 

There are a wide variety of chemotherapy drugs available to treat cancer. At Scott & White, we use all the standard chemotherapies.

How Chemotherapy Is Used to Treat Cancer

Renal pelvis and ureter cancer is infrequently treated with chemotherapy. However, your physician team may recommend chemotherapy in some cases in addition to or instead of other treatments for your renal pelvis and ureter cancer.

Chemotherapy is a form of cancer treatment where drugs are injected, given orally or through an IV, to keep your cancer from spreading. Often chemotherapy drugs are used in combination to attack cancer cells. It’s usually given in cycles over several months.

Chemotherapy is used in some cases:

  • In combination with radiation therapy to treat metastatic cancer (cancer that has spread)
  • For high-risk disease

There are a wide variety of chemotherapy drugs available to treat cancer. At Scott & White, we use all the standard chemotherapies.

Intravesical Therapy

At Scott & White, we offer intravesical therapy for the treatment of renal pelvis and ureter cancer. Intravesical therapy is a form of local chemotherapy, where your urologisst inserts chemotherapy drugs directly into your bladder through a thin tube (catheter).

Intravesical therapy is a good choice for patients with early-stage renal pelvis and ureter cancer. This form of chemotherapy has fewer side effects than traditional chemotherapies.

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Side Effects of Chemotherapy

Each chemotherapy drug is different and each person’s reaction to it can vary. At Scott & White, your medical oncologist will see you through treatment and help you manage any side effects.

Here are some common side effects of chemotherapy drugs for cancer of the renal pelvis and ureter:

  • Fatigue
  • Hair loss
  • Mouth sores
  • Loss of appetite
  • Bruising or bleeding
  • Nausea and vomiting
  • Diarrhea or constipation
  • Lowered resistance to infection

For more information about possible side effects, please talk to your medical oncologist.


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