Pick's Disease

Pick's disease is a form of dementia. It causes a slow progressive deterioration of social skills and changes in personality, along with impairment of intellect, memory, and language. Patients typically have atrophy of the frontal and temporal lobes of the brain. Some nerve cells have characteristic abnormalities when viewed under a microscope.


The cause of the disease is unknown.


The disease varies greatly in the way it affects individuals. But there is a common core of symptoms among patients which may be present at different stages of the disease. These symptoms include:

  • Loss of memory.

  • Lack of spontaneity.

  • Difficulty in thinking or concentrating.

  • Disturbances of speech.

Other symptoms include:

  • Gradual emotional dullness.

  • Loss of moral judgment.

  • Progressive dementia.

The disease usually affects individuals between the ages of 40 and 60. The age of onset may range from 20 to 80.


There is no cure or specific treatment for Pick's disease. Its progression cannot be slowed, but some of the symptoms of the disease may be treated effectively.

The course of Pick's disease is a progressive deterioration. The length of progression varies. It ranges from less than 2 years in some to more than 10 years in others. Death is usually caused by infection.