Opsoclonus Myoclonus

Opsoclonus myoclonus is a rare neurological disorder.


Its symptoms include:

  • Unsteady walk (gait).

  • Rhythmic, involuntary motions of the arms and legs. This occurs during voluntary movements such as reaching. It is called intention tremor.

  • Brief, shock-like muscle spasms. (myoclonus).

  • Irregular, rapid, horizontal and vertical eye movements. This is known as opsoclonus.

  • Poorly spoken speech. This is called dysarthria.

  • Inability to speak. This is called mutism.

  • Decreased muscle tone. This is known as hypotonia.

  • Lethargy.

  • Irritability.

  • A vague feeling of bodily discomfort (malaise).

  • Difficulty speaking. This is called dysphasia.

This disorder may occur with:

  • Tumors.

  • Viral infections.


Treatment may include:

  • Corticosteroids.

  • ACTH (adrenocorticotropic hormone).

In cases where a tumor is present, other treatment may be required. It may include:

  • Chemotherapy.

  • Surgery.

  • Radiation.

Treatment of the underlying cause of the disorder may improve symptoms. Unexplained lack of disease activity may also occur. This is known as spontaneous remissions. Generally the disorder is not fatal. It does not cause death.