Liver Profile

A liver profile is a battery of tests which helps your caregiver evaluate your liver function. The following tests are often included in the liver profile:

Alanine aminotransferase (ALT or SGPT) This is an enzyme found primarily in the liver. Abnormalities may represent liver disease. This is found in cells of the liver so when it is elevated, it has been released by damaged cells.

Albumin – The serum albumin is one of the major proteins in the blood and a reflection of the general state of nutrition. This is low when the liver is unable to do its job. It is also low when protein is lost in the urine.

NORMAL FINDINGS

Adult/Elderly

  • Total protein: 6.4-8.3 g/dL or 64-83 g/L (SI units)

  • Albumin: 3.5-5 g/dL or 35-50 g/L (SI units)

  • Globulin: 2.3-3.4 g/dL

  • Alpha1 globulin: 0.1-0.3 g/dL or 1-3 g/L (SI units)

  • Alpha2 globulin: 0.6-1 g/dL or 6-10 g/L (SI units)

  • Beta globulin: 0.7-1.1 g/dL or 7-11 g/L (SI units)

Children

  • Total protein

  • Premature infant: 4.2-7.6 g/dL

  • Newborn: 4.6-7.4 g/dL

  • Infant: 6-6.7 g/dL

  • Child: 6.2-8 g/dL

  • Albumin

  • Premature infant: 3-4.2 g/dL

  • Newborn: 3.5-5.4 g/dL

  • Infant: 4.4-5.4 g/dL

  • Child: 4-5.9 g/dL

Albumin/Globulin ratio - Calculated by dividing the albumin by the globulin. It is a measure of well being.

Alkaline phosphatase – This is an enzyme which is important in diagnosing proper bone and liver functions.

NORMAL FINDINGS

Age / Normal Value (units/L)

  • 0-5 days / 35-140

  • Less than 3 yr / 15-60

  • 3-6 yr / 15-50

  • 6-12 yr / 10-50

  • 12-18 yr / 10-40

  • Adult / 0-35 units/L or 0-0.58 microKat/L (SI Units) (Females tend to have slightly lower levels than males)

  • Elderly / Slightly higher than adults

Aspartate aminotransferase (AST or SGOT) - an enzyme found in skeletal and heart muscle, liver and other organs. Abnormalities may represent liver disease. This is found in cells of the liver so when it is elevated, it has been released by damaged cells.

Bilirubin, Total: A chemical involved with liver functions. High concentrations may result in jaundice. Jaundice is a yellowing of the skin and the whites of the eyes.

NORMAL FINDINGS

Blood

  • Adult/elderly/child

  • Total bilirubin: 0.3-1.0 mg/dL or 5.1-17 micromole/L (SI units)

  • Indirect bilirubin: 0.2-0.8 mg/dL or 3.4-12.0 micromole/L (SI units)

  • Direct bilirubin: 0.1-0.3 mg/dL or 1.7-5.1 micromole/L (SI units)

  • Newborn total bilirubin: 1.0-12.0 mg/dL or 17.1-205 micromole/L (SI units)

  • Urine 0-0.02 mg/dL

Ranges for normal findings may vary among different laboratories and hospitals. You should always check with your doctor after having lab work or other tests done to discuss the meaning of your test results and whether your values are considered within normal limits

PREPARATION FOR TEST

No preparation or fasting is necessary unless you have been informed otherwise. A blood sample is obtained by inserting a needle into a vein in the arm.

MEANING OF TEST

Your caregiver will go over the test results with you and discuss the importance and meaning of your results, as well as treatment options and the need for additional tests if necessary.

OBTAINING THE TEST RESULTS

It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.