Fructosamine

This is a test used to help monitor your diabetes over time, especially when it is not possible to monitor using the A1C test. It helps determine the effectiveness of changes to your diabetic treatment plan. It measure your average blood glucose level over a 2-3 week period.

The fructosamine test is a measurement of glycated protein. When glucose levels in the blood are elevated over a period of time, glucose molecules permanently combine with hemoglobin found inside the red blood cells (RBC's) and with albumin and other serum proteins, a process called glycation. The more glucose that is present, the greater the amount of glycated hemoglobin and glycated protein formed. These combined molecules persist for the life of the RBC or the protein and provide a record of the average amount of glucose that has been present in the blood over that time period. Since RBC's live for about 120 days, glycated hemoglobin (hemoglobin A1C) reveals average blood glucose levels over the past 2 to 3 months. Serum proteins have a shorter lifespan, about 14 to 21 days, so glycated proteins reflect average glucose levels over a 2 to 3 week time period.

Keeping blood glucose levels as close as possible to normal allows diabetic patients to avoid many of the complications and progressive damage associated with elevated glucose levels. Good diabetic control is achieved and maintained by daily (or even more frequently) self-monitoring of glucose levels and by occasional monitoring of the effectiveness of treatment using either a fructosamine or A1C test.

PREPARATION FOR TEST

A blood sample is obtained by inserting a needle into a vein in the arm.

NORMAL FINDINGS

Normal ranges vary according to method.

Ranges in children are slightly lower than those in adults.

  • Non-diabetics: 1.5-2.7 mmol/L

  • Diabetics: Greater Than 2.0-5.0 mmol/L depending on the degree of control

Ranges for normal findings may vary among different laboratories and hospitals. You should always check with your doctor after having lab work or other tests done to discuss the meaning of your test results and whether your values are considered within normal limits.

MEANING OF TEST

Your caregiver will go over the test results with you and discuss the importance and meaning of your results, as well as treatment options and the need for additional tests if necessary.

OBTAINING THE TEST RESULTS

It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.