Epstein-Barr Virus Titer

This is a blood test used to detect Epstein-Barr virus. Once the infection occurs, it can become dormant and may affect the person later. It can produce infectious mononucleosis, which is seen most often in children, adolescents, and young adults. Most persons with this will recover within 4 to 6 weeks and can return to normal activity. The EBV will often have symptoms such as fatigue, fever, sore throat, enlarged lymph glands, or enlarged spleen. It also affects the lymphocytes (one of the white blood cells). Once infected, the person will be a lifelong carrier of the virus.

PREPARATION FOR TEST

No preparation or fasting is necessary.

NORMAL FINDINGS

Titer less than 1:10 are nondiagnostic.

Titers of 1:10 1:60 indicate infection at some undetermined time.

Titers of 1:320 or greater suggest active infection.

Fourfold increase in titer in paired sera drawn 10 to 14 days apart is usually indicative of an acute infection.

Ranges for normal findings may vary among different laboratories and hospitals. You should always check with your doctor after having lab work or other tests done to discuss the meaning of your test results and whether your values are considered within normal limits.

MEANING OF TEST

Your caregiver will go over the test results with you and discuss the importance and meaning of your results, as well as treatment options and the need for additional tests if necessary.

OBTAINING THE TEST RESULTS

It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.