Digoxin Toxicity

Digoxin is a medicine that can help a weakened heart to function properly. Digoxin increases the strength of the heart muscle, helps to maintain a normal heart rhythm, and helps to remove excess water from the body. Digoxin can relieve symptoms of heart failure. Heart failure is a condition that reduces the ability of the heart to pump enough blood through the body. Symptoms that digoxin can relieve include swelling of the feet and legs, difficulty breathing, and extreme tiredness or weakness.

Digoxin is a good medicine for helping the heart. However, if too much medicine is taken, it acts like a poison (toxic). The body may begin to overreact or have side effects from the dose.


  • Anxiousness or nervousness.

  • Changes in color vision (more yellow color), blurred vision, eyes sensitive to light, light flashes, or halos around bright lights.

  • Changes in behavior, mood, mental ability, or confusion.

  • Chest pain or irregular heartbeats (palpitations).

  • Diarrhea or constipation.

  • Dizziness or drowsiness.

  • Fainting spells, fast or irregular heartbeat (more likely in children).

  • Headache.

  • Irregular, slow heartbeat (less than 50 beats per minute).

  • Loss of appetite, feeling sick to your stomach (nausea), vomiting, or stomach pain.

  • Skin rash or itching.

  • Tingling or numbness in the hands or feet, unusual bruising, or pinpoint red spots on the skin.

  • Weakness or tiredness.

  • Breast enlargement in men and women and sexual problems such as impotence.


  • If you miss a dose, take it as soon as you can. If it is nearly time for your next dose, take only that one dose. Do not take double or extra doses.

  • Swallow medicines with water. It is best to take digoxin on an empty stomach, at least 1 hour before or 2 hours after meals. Take your doses at regular intervals. Do not take your medicine more often than directed.

  • Tell your caregiver about all other medicines you are taking, including nonprescription medicines, nutritional supplements, or herbal products.

  • Tell your caregiver if you frequently have drinks with caffeine or alcohol, you smoke, or you use street drugs. This may affect the way your medicine works. Check with your caregiver before stopping or starting any of your medicines.

  • Watch your diet. Less digoxin may be absorbed from the stomach if you have a diet high in bran fiber.

  • If you are going to have surgery, tell your caregiver that you are taking digoxin.

  • Do not take antacids or treat yourself with nonprescription medicines for pain, allergies, coughs, or colds without advice from your caregiver.

  • Check your heart rate and blood pressure regularly. Ask your caregiver what your heart rate and blood pressure should be and when you should contact him or her. You may also need regular blood tests and tests to record the electrical activity of the heart (electrocardiography, EKG).

Digoxin tablets are easily confused with other look-alike tablets. If you take other tablets that look similar, ask your pharmacist how to avoid mix-ups and complications.


  • You develop chest pain or shortness of breath.

  • You have fainting spells, or a fast or irregular heartbeat.

  • You have a slow heartbeat (less than 50 beats per minute).


  • Understand these instructions.

  • Will watch your condition.

  • Will get help right away if you are not doing well or get worse.