AMA, Mitochondrial Antibody

This is a test to help diagnose primary biliary cirrhosis (PBC). This test measures the amount of antimitochondrial antibodies (AMA) in the blood. The production of AMA is strongly associated with primary biliary cirrhosis (PBC). PBC is an autoimmune disorder that causes inflammation and scarring of the bile ducts inside the liver. It is found most frequently in women between the ages of 35 and 60. PBC blocks the flow of bile (a fluid produced in the liver that helps digest fats) and causes progressive liver damage. About 94% of those affected by PBC will have significant concentrations of antimitochondrial antibodies.

PREPARATION FOR TEST

No preparation or fasting is necessary. A blood sample is taken by a needle from a vein.

NORMAL FINDINGS

Negative

Ranges for normal findings may vary among different laboratories and hospitals. You should always check with your doctor after having lab work or other tests done to discuss the meaning of your test results and whether your values are considered within normal limits.

MEANING OF TEST

Your caregiver will go over the test results with you and discuss the importance and meaning of your results, as well as treatment options and the need for additional tests if necessary.

OBTAINING THE TEST RESULTS

It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.