Serum Angiotensin Converting Enzyme (ACE, SACE)

Angiotensin converting enzyme (ACE) is an enzyme produced in the body to help regulate blood pressure. This test is mainly ordered to help diagnose and monitor sarcoidosis. It is often ordered as part of an investigation into long-standing problems that may or may not be due to sarcoidosis. ACE will be elevated in 50% to 80% of patients with active sarcoidosis. If it is initially elevated in someone with sarcoidosis, it can be ordered at regular intervals to monitor the course of the disease and the effectiveness of corticosteroid treatment.


People taking steroids should talk to their doctor, because taking steroids can decrease ACE levels. A blood sample is taken by a needle from a vein.


Less than 40 micrograms/L or Less than 670 nKat/L (SI Units)

Ranges for normal findings may vary among different laboratories and hospitals. You should always check with your doctor after having lab work or other tests done to discuss the meaning of your test results and whether your values are considered within normal limits.


Your caregiver will go over the test results with you and discuss the importance and meaning of your results, as well as treatment options and the need for additional tests if necessary.


It is your responsibility to obtain your test results. Ask the lab or department performing the test when and how you will get your results.