Jason H. Huang, MD, FACS

Baylor Scott & White Health

Chair, Department of Neurosurgery

Neurosurgery, Spinal Surgery

Patient Care Emphasis
Brachial Plexus and Peripheral Nerve Surgery, Brain Abscess, Hydrocephalus, Low Back Pain - Chronic, Skull Base Tumors, Spinal Tumors, Spine Disc Herniations, Traumatic Brain Injury, Trigeminal Neuralgia, Tumor

Board Certification
  • Diplomate American Board of Neurological Surgery

  • Baylor Scott & White Appointment
    January 6, 2014

  • Johns Hopkins University School of Medicine, Baltimore, MD, MD, 1995-1999
  • Amherst College, Amherst, MA, BA, magna cum laude, 1992-1994

  • Specialty Training
  • Complex Spine Fellowship, University of Pennsylvania, Philadelphia
  • Neurosurgery Residency, University of Pennsylvania
  • Neurotrauma & Critical Care Fellowship, University of Pennsylvania

  • Faculty Rank - Texas A&M Health Science Center College of Medicine
    Professor of Surgery

    Publications and Research
  • Sonabend, A.M., Smith, P., Huang, J.H., Winfree, C.. "Peripheral Nerve Injury". Schmidek & Sweet Operative Neurosurgical Techniques. Quinones-Hinojosa A.. Philadelphia: W.B. Sanders, 2012. 2225-2238
  • Waldau, B., Huang, J.H., Winn, H.R., Grant, G.A.. "Blast-induced Neurotrauma". Youmans Neurological Surgery. H. Richard Winn. Philadelphia: Elsevier, 2011. 3465-3469
  • Groff, R. F.; Huang, J. H.. "Thoracic Outlet Compression Syndrome". Encyclopedic Reference of Molecular Mechanisms of Disease. Lang, F.. Heidelberg: Springer-Verlag, 2009.
  • Huang, J. H.; Whitmore, R. G.; Zager, E. L.. "Obturator Nerve Injury and Repair". Surgery of Peripheral Nerves: A Case Based Approach. Midha, R.; Zager, E.L.. New York: Thieme Medical Publishers, 2008. 171-174
  • Huang, J.H.; Whitmore, R.G.; Zager, E.L.;. "Carpal Tunnel Release". Neurosurgical Operative Atlas: Spine and Peripheral Nerves. Wolfa, C.E.; Resnick, D.K.;. New York: Thieme, 2007. 317-322
  • Durham, S.R.; Huang, J.H.;. "Surgical Management of Sciatic Nerve Lesions". Schmidek & Sweet Operative Neurosurgical Techniques: Indications, Methods, and R. Schmidek, H.H.; Roberts, D.W.;. Philadelphia: W.B. Saunders, 2005. 2319-2323
  • Wang F, Smith NA, Xu Q, Goldman S, Peng W, Huang JH, Takano T, Nedergaard M. "Photolysis of caged Ca2+ but not receptor-mediated Ca2+ signaling triggers astrocytic glutamate release." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2013 Oct 30; 33(44):17404-12.
  • Wang EW, Huang JH. "Understanding and treating blast traumatic brain injury in the combat theater." Neurological research. 2013 Apr 0; 35(3):285-9. Epub 2012 Dec 28.
  • Huang JH. "Traumatic brain injury." Neurological research. 2013 Apr 0; 35(3):221-2.
  • Tong J, Liu W, Wang X, Han X, Hyrien O, Samadani U, Smith DH, Huang JH. "Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice." Journal of neurotrauma. 2013 Feb 15; 30(4):247-58. Epub 2013 Feb 04.
  • Gao W, Xu H, Liang M, Huang JH, He X. "Association between reduced expression of hippocampal glucocorticoid receptors and cognitive dysfunction in a rat model of traumatic brain injury due to lateral head acceleration." Neuroscience letters. 2013 Jan 15; 533:50-4. Epub 2012 Nov 28.
  • Liu X, Tian W, Kolar B, Hu R, Huang Y, Huang J, Ekholm S. "Advanced MR diffusion tensor imaging and perfusion weighted imaging of intramedullary tumors and tumor like lesions in the cervicomedullary junction region and the cervical spinal cord." Journal of neuro-oncology.. 2013 Epub 2013 Dec 30.
  • Algattas H; Huang JH. "Neurotrauma and Repair Research: Traumatic Brain Injury (TBI) and its Treatments". Biomedical Engineering and Computational Biology. 2013; 5: 51-56.
  • Algattas H, Huang JH. "Traumatic brain injury pathophysiology and treatments: early, intermediate, and late phases post-injury." International journal of molecular sciences. 2013 15(1):309-41. Epub 2013 Dec 30
  • Liu W, Ren Y, Bossert A, Wang X, Dayawansa S, Tong J, He X, Smith DH, Gelbard HA, Huang JH. "Allotransplanted neurons used to repair peripheral nerve injury do not elicit overt immunogenicity." PloS one. 2012 7(2):e31675. Epub 2012 Feb 09.
  • Yang AI, Balser DS, Mikheev A, Offen S, Huang JH, Babb J, Rusinek H, Samadani U. "Cerebral atrophy is associated with development of chronic subdural haematoma." Brain injury : [BI]. 2012 26(13-14):1731-6. Epub 2012 Jul 03
  • Johnson NE, Petraglia AL, Huang JH, Logigian EL. "Rapid resolution of severe neuralgic amyotrophy after treatment with corticosteroids and intravenous immunoglobulin." Muscle & nerve. 2011 Aug 0; 44(2):304-5. Epub 2011 Jun 29.
  • Han X, Tong J, Zhang J, Farahvar A, Wang E, Yang J, Samadani U, Smith DH, Huang JH. "Imipramine treatment improves cognitive outcome associated with enhanced hippocampal neurogenesis after traumatic brain injury in mice." Journal of neurotrauma. 2011 Jun 0; 28(6):995-1007. Epub 2011 May 12.
  • Farahvar A, Huang JH, Papadakos PJ. "Intracranial monitoring in traumatic brain injury." Current opinion in anaesthesiology. 2011 Apr 0; 24(2):209-13.
  • Tong J, Latzman JM, Rauch J, Zagzag DS, Huang JH, Samadani U. "Sonic hedgehog agonist fails to induce neural stem cell precursors in a porcine model of experimental intracranial hemorrhage." Acta neurochirurgica. Supplement. 2011 111:151-4
  • Ranalli NJ, Huang JH, Lee EB, Zhang PJ, Siegelman ES, Zager EL. "Hemangiomas of the brachial plexus: a case series." Neurosurgery. 2009 Oct 0; 65(4 Suppl):A181-8.
  • Wu Q, Huang JH, Sampson ER, Kim KO, Zuscik MJ, O'Keefe RJ, Chen D, Rosier RN. "Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage." Experimental cell research. 2009 Aug 15; 315(14):2386-98. Epub 2009 May 27.
  • Huang JH, Cullen DK, Browne KD, Groff R, Zhang J, Pfister BJ, Zager EL, Smith DH. "Long-term survival and integration of transplanted engineered nervous tissue constructs promotes peripheral nerve regeneration." Tissue engineering. Part A. 2009 Jul 0; 15(7):1677-85.
  • Zhang J, Groff RF, Chen XH, Browne KD, Huang J, Schwartz ED, Meaney DF, Johnson VE, Stein SC, Rojkjaer R, Smith DH. "Hemostatic and neuroprotective effects of human recombinant activated factor VII therapy after traumatic brain injury in pigs." Experimental neurology. 2008 Apr 0; 210(2):645-55. Epub 2008 Jan 05.
  • Huang JH, Zager EL, Zhang J, Groff RF, Pfister BJ, Cohen AS, Grady MS, Maloney-Wilensky E, Smith DH. "Harvested human neurons engineered as live nervous tissue constructs: implications for transplantation. Laboratory investigation." Journal of neurosurgery. 2008 Feb 0; 108(2):343-7.
  • Kameswaran N, Cullen DK, Pfister BJ, Ranalli NJ, Huang JH, Zager EL, Smith DH. "A novel neuroprosthetic interface with the peripheral nervous system using artificially engineered axonal tracts." Neurological research. 2008 30(10):1063-7.
  • Johnson VE, Huang JH, Pilcher WH. "Special cases: mechanical ventilation of neurosurgical patients." Critical care clinics. 2007 April; 23(2):275-90.
  • Huang JH, Johnson VE, Zager EL. "Tumors of the peripheral nerves and plexuses." Current treatment options in neurology. 2006 Jul 0; 8(4):299-308.
  • Huang JH, Zhang J, Zager EL. "Diagnosis and treatment options for nerve sheath tumors." Expert review of neurotherapeutics. 2005 Jul 0; 5(4):515-23.
  • Huang JH, Samadani U, Zager EL. "Ulnar nerve entrapment neuropathy at the elbow: simple decompression." Neurosurgery. 2004 Nov 0; 55(5):1150-3.
  • Huang JH, Simon SL, Nagpal S, Nelson PT, Zager EL. "Management of patients with schwannomatosis: report of six cases and review of the literature." Surgical neurology. 2004 Oct 0; 62(4):353-61; discussion 361.
  • Huang JH, Zager EL. "Thoracic outlet syndrome." Neurosurgery. 2004 Oct 0; 55(4):897-902; discussion 902-3.
  • Huang JH, Samadani U, Zager EL. "Case studies for illustration and discussion: peripheral nerve tumors." Neurosurgery clinics of North America. 2004 Apr 0; 15(2):241-9, viii
  • Huang JH, Zager EL. "Mini-open carpal tunnel decompression." Neurosurgery. 2004 Feb 0; 54(2):397-9; discussion 399-400.
  • Huang JH, Tsui I, Judkins AR, Simon E, Birknes JK, Sutton LN. "Intramedullary cervical spine germinoma: case report." Neurosurgery. 2004 55(6):1432.
  • Huang, J. H.; Samadani, U.; Zager, E. L. "Brachial Plexus Region Tumors: A Review of Their History, Classification, Surgical Management, and Outcomes". Neurosurgery Quarterly. 2003; 13(3): 151-161.
  • Huang JH, Ali Z, Travison TG, Campbell JN, Meyer RA. "Spatial mapping of the zone of secondary hyperalgesia reveals a gradual decline of pain with distance but sharp borders." Pain.. 2000 May 0; 86(1-2):33-42.
  • Huang JH, Thalhammer JG, Raymond SA, Strichartz GR. "Susceptibility to lidocaine of impulses in different somatosensory afferent fibers of rat sciatic nerve." The Journal of pharmacology and experimental therapeutics. 1997 Aug 0; 282(2):802-11.
  • Waikar SS, Thalhammer JG, Raymond SA, Huang JH, Chang DS, Strichartz GR. "Mechanoreceptive afferents exhibit functionally-specific activity dependent changes in conduction velocity." Brain research. 1996 May 20; 721(1-2):91-100.
  • Wang F., Wang X., Shapiro L.A., Cotrina, M.L., Liu, W., Wang, E.W., Gu, S., Wang, W., He, X., Nedergaard, M., Huang, J.H.: NKCC1 up-regulation Contributes to Early Post-traumatic Seizures and Increased Post-traumatic Seizure Susceptibility. Brain Struct. Funct. 2017 Apr; 222(3):1543-1556 PMID: 27586142.
  • Alluri, H., Grimsley, M., Anasooya, S.C., Varghese, K.P., Zhang, S.L., Peddaboina, C., Robinson, B., Beeram, M.R., Huang, J.H., Tharakan, B.: Attenuation of Blood-Brain Barrier Breakdown and Hyperpermeability by Calpain Inhibition. J Biol Chem 291(53):26958-26969 Dec 30, 2016. PMID: 27875293.
  • Wu, Q., Huang, J.H.: Ectopic Expression of Smurf2 and Acceleration of Age-related Intervertebral Disc Degeneration in a Mouse Model. J Neurosurg Spine, April 7: 1-11, 2017. [Epub ahead of print] PMID: 28387615
  • Gestaut, MM, Thawani, N., Kim, S., Gutti, V.R., Jhavar, S., Deb, N. Morrow, A., Ward, R.A., Huang, J.H., Patel, M.: Single Fraction Spine Stereotactic Ablative Body Radiotherapy with Volumetric Modulated Arc Therapy. J Neurooncol. 2017 April 13 [Epub ahead of print] PMID: 28409420
  • Liang, B., Huang, J.H.: Elevated NKCC1 transporter expression facilitates early post-traumatic brain injury seizures. Neural Regen. Res. 12(3): 401-402, Mar 2017. PMID: 28469651
  • Wang, F., Yuan, T., Pereira A. Jr, Verkhratsky, A., Huang, J.H.: Glial Cells and Synaptic Plasticity, Neural Plasticity, 2016: 5042902, Epub May 17, 2016. PMID: 27293902.
  • Sone, J.Y., Kondziolka D., Huang, J.H., Samadani, U.: Helmet Efficacy against Concussion and Traumatic Brain Injury: A Literature Review, Journal of Neurosurgery, May 27:1-14, 2016, [Epub ahead of print]. PMID: 27231972
  • Dandashi, J.A., Nizamutdinov, D., Dayawansa, S., Fonkem, E., Huang, J.H.: Texas Occurrence of Lyme Disease and Its Neurological Manifestations. J Neuroinfect Dis 7(2). Pii:217. June 2016. PMID: 27478852.
  • Konda, S., Dayawansa, S., Huang, J.H.: The Evolution and Challenge of the Zika virus and its Uncharted Territory in the Neurological Realm. J Neuroinfect Dis 7(2). Pii:215. June 2016. PMID: 27478853.
  • Alluri, H., Wilson, R.L., Anasooya, S.C., Wiggins-Dohlvik, K., Patel, S., Liu, Y., Peng, X., Beeram, M.R., Davis, M.L., Huang, J.H., Tharakan, B.: Melatonin Preserves Blood-Brain Barrier Integrity and Permeability via Matrix Metalloproteinase-9 Inhibition, PLoS one, 11(5): e0154427, May 6, 2016. PMID: 27152411.
  • Tuner, R.C., Lucke-Wold, B.P., Logsdon, A.F., Robson, M.J., Dashnaw, M.L., Huang, J.H., Smith, K.E., Huber, J.D., Rosen, C.L., Petraglia, A.L.: The Quest to Model Chronic Traumatic Encephalopathy: A Multiple Model and Injury Paradigm Experience. Frontiers in Neurology. 2015 Oct 20;6:222. PMID 26539159
  • Ding, X., Ma, M., Teng, J., Teng, R.K., Zhou, S., Yin, J. Fonkem, E., Huang, J.H., Wu, E., Wang, X.: Exposure to ALS-FTD-CSF Generates TDP-43 Aggregates in Glioblastoma Cells Through Exosomes and TNTs-like Structure. Oncotarget 2015 Sept 15; 6(27):24178-91. PMID: 26172304
  • Samadani U., Ritlop, R., Reyes, M., Nehrbass, E., Li, M., Lamm, E., Schneider, J., Shimunov, D., Sava, M., Kolecki, R., Burris, P., Altomare, L., Mehmood, T., Smith, R.T., Huang, J., McStay, C., Todd, S.R., Qian, M., Kondziolka, D., Wall, S., Huang, P.: Eye Tracking Detects Disconjugate Eye Movements Associated with Structural Traumatic Brain Injury and Concussion. Journal of Neurotrauma, 32(8):548-556, April 15, 2015. PMID: 25582436
  • Markman, J., Kress, B.T., Frazer, M., Hanson, R., Kogan V., and Huang, J.H.: Screening for Neuropathic Characteristics in Failed Back Surgery syndromes: Challenges for Guiding Treatment, Pain Medicine, 16(3): 520-530, March 2015. PMID: 25530081.
  • Petraglia, AL, Plog, B.A., Dayawansa, S., Chen, M., Dashnaw, M.L., Czerniecka, K., Walker, C.T., Viterise, T., Hyrien, O., Iliff, J.J., Deane, R., Nedergaard, M., Huang, J.H.: The Spectrum of Neurobehavioral Sequelae Following Repetitive Mild Traumatic Brain Injury: A Novel Mouse Model of Chronic Traumatic Encephalopathy, Journal of Neurotrauma, 31(13):1211-1224, July 1, 2014. PMID 24766454.
  • Tong, J., Ren, Y., Wang, X., Dimopoulos V.G., Kesler, H.N., Liu, W., Nedergaard, M., Huang, J.H.: Assessment of NgR1 Function in vivo after Spinal Cord Injury, Neurosurgery, 2014 July; 75(1):51-60. PMID: 24594926
  • Little, DM; Geary, EK; Moynihan, M; Alexander, A; Pennington, M; Glang, P; Schulze, ET; Dretsch, M; Pacifico, A; Davis, ML; Stevens, AB; Huang, JH. “Imaging Chronic Traumatic Brain Injury as a Risk Factor for Neurodegeneration.” Alzheimer’s & Dementia, 10 (3 Suppl):S188-195, June, 2014. PMID: 24924670.

  • Awards and Honors
  • Sigma Xi Scientific Research Society, Amherst College Chapter, Amherst, MA
  • John Woodruff Simpson Fellowship in Medicine
  • Alpha Omega Alpha National Research Fellowship, Washington, D.C.
  • Second Place Outstanding Poster Presentation Award-Spine, New Orleans, LA
  • Codman Award, Section of Neurotrauma and Critical Care of the AANS, Rolling Meadows, IL
  • David G. Kline Award, Section of Spine and Peripheral Nerve of the AANS
  • Charles Elsberg Award, New York Academy of Medicine, New York, NY
  • Young Clinician Investigator's Award, Neurosurgery Research Education Foundation of the AANS
  • The Army Commendation Medal, United States Army
  • Best Research Presentation Award, Pennsylvania Neosurgical Society Annual Meeting, Hershey, PA
  • Henry Strong Denison Award for Excellence in Research, Johns Hopkins University, Baltimore, MD
  • Compassionate Doctor Recognition, Vitals.com
  • Patients' Choice Award, Vitals.Com
  • "Super Doctor," Texas Monthly, 2015
  • "Super Doctor," Texas Monthly, 2016

  • Professional Memberships
  • Society for Neuroscience
  • Congress of Neurological Surgeons
  • American Association of Neurological Surgeons
  • American Medical Association
  • Neurosurgical Society of America

  • Languages Spoken
    English, Mandarin

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